The Toll-like receptors (TLRs) and retinoic-acid-inducible gene I (RIG-I)-like receptors (RLRs) both participate in sensing viral infection, but do so in different cells and fill different 'niches'.

November 24, 2025 • Our annual reading guide returns with 380+ new titles handpicked by NPR staff and trusted critics. Find 13 years of recommendations all in one place — that's more than 4,000 great ...