How is it that your body with all of its specialized organs developed from a single cell? Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology ...

Epigenome editing has followed a similar path, in that more recent technological breakthroughs have enabled scientists to apply the discoveries made in previous decades. Epigenome editing performs a ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Evolution is traditionally associated with a process of increasing complexity and gaining new genes. However, the explosion of the genomic era shows that gene loss and simplification is a much more ...

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells ...

Dr. Ju-Gyeong Kang, Ph.D candidate TaeJun Seol, Professor Dae-Sik Lim >Metabolic diseases such as obesity, fatty liver, and insulin ...

DNA provides the foundational library of possibilities, but the environment serves as the librarian, choosing which books are ...