Google DeepMind has unveiled a new artificial intelligence tool, AlphaGenome, aimed at helping scientists identify genetic changes that trigger diseases and accelerate the development of new ...
A Ludwig Cancer Research study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome—one that contributes to many genetic diseases, ...
Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.
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Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the ...
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Engineered enzymes enable precise control of mitochondrial DNA mutation levels in cells
Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes. Some of these conditions result from ...
A microfluidic device barely larger than a U.S. quarter and developed by a Rutgers University-led team can detect rare genetic mutations from a single drop of blood. A team led by Rutgers ...
In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...
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